Dual use of AI-powered drug discovery (2022)¶
Reference
Citation: Urbina, F., Lentzos, F., Invernizzi, C. & Ekins, S. "Dual use of artificial-intelligence-powered drug discovery." Nature Machine Intelligence 4, 189-191 (2022). Type: paper. Link: doi:10.1038/s42256-022-00465-9.
What it is¶
A toxicity-prediction model was inverted to design toxic molecules. It generated 40,000 candidate toxic molecules, including VX and other known chemical-warfare agents, in under 6 hours.
Role in the record¶
- Grounds BP10: the sharpest non-life-science instance that dual-use misuse capability is real, supporting screening before an agent is given reach.
Atom-level for/against detail and quotes are in the provenance data (assets/provenance.yml), keyed by practice atom.